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Por otra parte el uso de benzodiazepinas puede conducir a una dependencia, principalmente cuando se toma el medicamento de forma ininterrumpida durante largo tiempo. No se recomienda, en basic, interrumpir bruscamente la medicación, de acuerdo siempre con las instrucciones del médico.I favor purchasing from them in bulk (unique medicines I might require from the portions needed), mainly because like that It can save you lots of money and stay clear of purchasing for anything each and every time you may need it.
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Particular manufacturers of this medication can not be utilized with dairy products. Do not crush, crack, or open a delayed-launch capsule, consume the capsule total. Whether it is an oral suspension shake it in advance of use and evaluate with Specific measuring spoon. Never ever consider this drug whether it is expired as it could hurt your kidney.
El estado estacionario se alcanza en aproximadamente 5 dÃas; mientras que para el metabolito desmetil-diazepam tardan aproximadamente el doble en alcanzar un estado estacionario.
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Las benzodiazepinas pasan a la leche materna, por lo que deberá consultar con su médico la toma o no de Valium mientras esté en periodo de lactancia.
La revisión de la notificación espontánea de eventos adversos no muestra una mayor incidencia que los que se esperarÃan de una población very similar no tratada. Las benzodiazepinas deben evitarse durante el embarazo a menos que no exista una alternativa más segura.
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Se deben monitorizar las constantes vitales del paciente y establecer medidas de soporte en función de su estado clÃnico.
El metabolismo de diazepam está mediado por las isoenzimas del citocromo P450; principalmente CYP2C19 y CYP3A las responsables del metabolito desmetil-diazepam y CYP3A en la formación de temazepam y oxazepam.